You can pick which dice you want to use. While in a regular room, the chances to spawn a Red Room are: 1 Key = 33.33% chance. If you didn't find one before this point, there will be a tinted Skull somewhere on Depths II, which contains a Fool card when blown up. Upon use, this item summons a ghost near Isaac that will follow him around. The longer the button is held the faster Gurdy will fling itself across the screen, Deals a fixed amount of damage depending on charge level, at lowest being ~5 and at max being ~20, Lil Gurdy bounces off of enemies and obstacles, A beggar head which floats around the room and picks up any nearby coins. See the dedicated Devil room page for more details, Reveals the entire map and shows the icons for every room which has one, This is completely useless if you currently have both the Treasure Map and The Compass, Doubles your current red hearts up to full health, * , the lost item pool, playing, card, white, red, When used, turns all pickups, chests and non-boss enemies in the room into Bombs, UNLOCK: Unlock this item by getting a 3 win streak, When used, turns all pickups, chests and non-boss enemies in the room into Coins, UNLOCK: Unlock this item by defeating The Lamb in under 20 minutes, When used, turns all pickups, chests and non-boss enemies in the room into Keys, UNLOCK: Unlock this item by defeating The Lamb without taking hearts, coins and bombs, When used, turns all pickups, chests and non-boss enemies in the room into Hearts, UNLOCK: Unlock this item by defeating any floor after Basement I with only half a heart of health (works as The Lost), Teleports you to the Devil Deal Room on the current floor, When used, instantly kills you and spawns 10 pickup on the floor, Each of the 10 things spawned can be any type of consumable or sometimes a pedestal item (up to a maximum of 3 pedestal items), Any pedestal item created by Suicide King will be related to the room where it was used, meaning that using it in the Angel room will spawn Angel room items, UNLOCK: Unlock this card by beating Challenge #7 (Suicide King), UNLOCK: Unlock this card by defeating Mega Satan as Tainted Magdalene, A card which can be thrown as a projectile directly infront of Isaac, instantly killing anything it hits, including most bosses, If thrown at a multi-phase boss with multiple forms such Satan, Mega Satan or Hush it will only kill that particular phase of the boss, If thrown at a multi-phase boss that works from a single health bar such as Isaac, ??? Finding all the puzzle pieces will help you to reveal the final secret, unlocking the hidden character 'The Lost', If held when you touch the chest after the Satan or Isaac fight and you don't have the relevant item to go to the next floor (Polaroid or Negative), you have a small chance to be taken there anyway, UNLOCK: Unlock this item by beating the Chest with Eden, 80% of heart drops are replaced with keys, Hearts turn into black hearts where possible. - Destroys all poops in the room and spawns a blue attack spider on every destroyed poop, Infested? Using the Red Key near it will spawn a red room, This room will randomly choose from many types, including (but not limited to) any regular room from that floor, treasure rooms, curse rooms, devil rooms, angel rooms, I AM ERROR rooms and more, In rooms with multiple door outlines, the closest one will be opened, Attempting to create a room outside the maximum boundary (13 x 13 rooms) of the map will take you to an I AM ERROR room. . Counts as 1 of 3 fly items needed towards the Beelzebub transformation. 2 keys = 16.6% chance. Counts as 1 of 3 familiar items needed towards the Conjoined transformation. Join. The effect triggers again 30 seconds after use and again 60 seconds after use, Something's wrong - Spawns a pool of black creep beneath Isaac, Vurp! You can force spawn a cracked key by droping any trinket in a Boss Room or Item room, on any floor on your way down to Depths II. rocks), Item Pool: Item Room, Devil Room, Greed Mode Devil Room, * item room, treasure room, item room pool, luigi board, weeja board, paper, grown, Automatically gives you 1 bar of charge after using your spacebar item, Fully recharges your current spacebar item when picked up, Any items which are normally a 1 room recharge are now timed instead, * shop room pool, shop item pool, battery, black, brown, When Isaac takes damage, the dead bird will spawn and attack nearby enemies in the current room for 2 damage per tick, * item room, treasure room, item room pool, the lost item pool, starting, grey, gray, Tears are replaced with the ability to charge and fire a powerful laser that travels in a straight line across the room, dealing a lot of damage (tear damage hits for 9 ticks per laser) to any enemies it comes into contact with, Does not directly affect your Damage stat but hits enemies 9 times per charge, Synergizes very well with a lot of items including Tammy's Head, Tiny Planet, Inner Eye (Triple Shot), Mutant Spider (Quad Shot) and many others, If you somehow manage to get a second Brimstone, the laser becomes massive and deals double damage, * devil pool, devil room pool, devil deal, infinity, red, black, Has a chance to drop while playing any Blood Donation machine, UNLOCK: Unlock this item by playing the Blood Donation machine 30 times, Item Pool: None (Blood Donation machine only), Gives you a high rate of fire in exchange for a damage down, * secret room pool, item room, treasure room, item room pool, Thin Odd Mushroom, brown, purple, grey, gray, REPENTANCE - Odd Mushroom (thick) is now a larger damage increase (equal to that of Steven/Pentagram), but now also a larger speed downgrade (from -0.1 to -0.2), * secret room pool, item room, treasure room, item room pool, purple, pink, brown, thick odd mushroom thick, When you only have half a red heart remaining or less, you enter a curse state which adds +1.5 damage and +0.3 speed, When playing as Eve, this item activates with one FULL heart remaining or less AND also removes her 0.75 damage multiplier, raising it up to 1.0, The effect is permanently active for characters with no red hearts (e.g. 8 coins = Slot Machine, While playing as Tainted Cain you get a visual interface to see what items are in the bag, allowing you to see what item will be created and swap out specific consumables, Has other uses - Will deal 3 damage to enemies it hits, and can be used to quickly push bombs and objects across rooms, Tainted Cain starts with this item, but can be used by any character after unlocking it and finding it in the item room, Cannot be used to craft another Bag of Crafting, UNLOCK: Unlock this item by defeating Delirium as Tainted Cain, While holding flip, a ghost item will appear behind item pedestals upon entering Item Rooms and Shop that cannot be interacted with, When activated, all real items in the room will be swapped with the ghost items behind them, The ghost item stays there even if you take the regular item, allowing you to use Flip to get both of them, Does nothing with item pedestals that don't have a ghost item behind them, When playing as Tainted Lazarus, activating Flip also changes you between Lazarus and Dead Lazarus, Tainted Lazarus starts with this item, but can be used by any character after unlocking it and finding it in the item room, UNLOCK: Unlock this item by defeating Delirium as Tainted Lazarus, When used, gives you an orbital flame which represents another random passive item in the game. It also doesn't do poison damage despite having the tagline 'toxic aura tears', * item room, treasure room, item room pool, brown, pink, purple, plant, Upon entering every 4th unexplored room, the Broken Watch will either slow down or speed up all enemies in the room, The slow effect is much more common than the speed up, * shop room pool, shop item pool, blue, grey, gray, smashed, clock, broken stop watch, broken stopwatch, A blue boomerang which can be thrown in a similar fashion to Mom's Knife, to stun any enemies it hits and deal damage, The damage dealt by the Boomerang is equal to double your tear damage, The boomerang can also be used to grab pickups and consumables from a distance, similar to the legend of zelda boomerang, The range of the boomerang is affected by range, with number one the distance is very short and makes the item a lot less effective, The Boomerang can be used to kill shopkeeper corpses, allowing you to farm their drops for coins, items, Steam Sale etc, REPENTANCE - Boomerang is now piercing, and has far less downtime between throwing it and being able to fire tears again, * shop room pool, shop item pool, crescent, moon, blue, grey, gray, * boss room pool, boss room item, grey, gray, punk, Decreases the size of Isaac, and your player hitbox, making you less likely to be hit, * boss room pool, boss room item, pro plus, tablet, medicine, white, * boss room pool, boss room item, grey, orange, family, picture, * boss room pool, boss room item, mushroom, fungi, fungus, Item Pool: Boss Room, Gold/Stone Chest, Key Beggar, * boss room pool, boss room item, brass, bronze, brown, gold, REPENTANCE - Also drops the Match Stick trinket, * boss room pool, boss room item, white, red, * boss room pool, boss room item, syringe, needle, grey, purple, pink, * boss room pool, boss room item, the lost item pool, dog, biscuit, brown, orange, A one-time use item which when used, will duplicate any pedestal items or consumables in the current room, If used in a shop, the duplicated items can be taken for free, If used on a trinket, another random trinket will spawn instead of a duplicate, If used in the Boss Rush, all the duplicates can be taken for free as well as one of the original items, If used in a Devil Room or Black Market, the duplicates can be taken for free, When used, copies the effect of the pill you are currently holding without consuming it, The charge time of this item depends on the quality of the pill you're holding, When used, has a 50% chance to drop one random type of coin (penny, nickel or dime), UNLOCK: Unlock this item by donating 33 coins to the Greed Donation Machine, UNLOCK: Keeper starts with this item after beating Isaac with Keeper, With this item, at the start of every room you will deal double your tear damage to the entire room in a poison effect, Enemies killed now also leave a pool of creep on the ground where they died. e.g. It returns after a room has been cleared, UNLOCK: Unlock this item by beating Greed Mode with Eden, Item Pool: Item Room, Secret Room, Greed Mode Shop, *, red, yellow, green, white, square, rectangle, When used, the D8 rerolls all of your stats, Will only effect your damage, tears, range and speed stats, Each stat is given a multiplier that applies after all other adjustments, UNLOCK: Unlock this item by beating Challenge #28 (Pride Day), * dice, pip, die, black, grey, gray, pyramid, triangle, Purity will boost one of Isaac's stats depending on the colour of the aura around him, When you take damage, the aura will be removed and replaced with another random one when you enter the next room, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Maggy, Item Pool: Item Room, Angel Room, Greed Mode Item Room, Greed Mode Angel Room, Adds a chance for a black ring to spawn around killed enemies, dealing damage to others that touch it, The ring damage scales with your tear damage, The change for a ring to spawn scales with your lucky stat, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Eve, Item Pool: Devil Room, Curse Room, Greed Mode Devil Room, *, grey, gray, silver, metal grabber, hand, robot, When Isaac has no red hearts, this item gives Isaac the ability to fly. It's a 20% chance on first miss, 33% for a second miss and 50% for anything beyond that, Piercing shots work with this item and multiple hits with a single tear will each give a damage bonus, *, bullseye, target, grey, gray, black, red, circle, Isaac has a random chance to fire a Holy tear, which when it hits an enemy, will spawn a light beam on the same enemy, dealing damage, The beams from this item deal damage equal to 400% of your tear damage (4x damage multiplier for the beams only), The chance to fire a Holy tear is affected by your luck stat, maxing out at a 50% chance, Item Pool: Item Room, Greed Mode Item Room, Angel Room, A familiar host that sits on Isaac's head and has a 20% chance to block enemy shots, When a shot is blocked, Host Hat will fire 3 bullets back at the enemy, Causes you to become immune to explosions, but doesn't protect against stomps or shockwaves, Causes your shops to instantly restock their items when you buy them, New items generated by Restock are from the shop item pool, The cost increases exponentially every time you purchase an item. This means you can leave rooms before defeating the enemies inside, Doesn't open locked doors, or the door that leads to the Boss Room, This item causes nearby enemies to be affected by the charm effect, causing them to attack other nearby enemies, The charm effect will wear off very quicky when enemies move away from Isaac, This item causes your tears to become rocks, which have increased knockback and can break other rocks and objects. 1 = poop, 2 = penny, 3 = bomb, 4 = key, 5 = red heart, 6 = pill, 7 = card, 8 = soul heart, 9 = gold heart, 10 = gold key, 11 = gold bomb, At the full 12 charges, a completely random effect will happen. ?, Satan and The Lamb as Tainted Apollyon, Gives you a red attack fly, that will charge at enemies in the same direction you are shooting, Deals damage equal to your current tear damage, Stops charging once it hits an enemy and returns to Isaac's side, UNLOCK: Unlock this trinket by defeating Mother as Tainted Apollyon, Gives a 33% chance to spawn an extra blind pedestal item in all future item rooms. - The Binding Of Isaac: Repentance #50; DOUBLE DEATH (CERTIFICATE)! Counts as 1 of 3 poop items needed towards the Oh Crap transformation. Taking it will cause Mom's Shadow to spawn and chase you. Taking a Devil deal breaks the cross and prevents the damage up next floor, Taking free pickups such as Black hearts in the Devil room also count, UNLOCK: Unlock this item by defeating The Beast as Judas, When you die, you turn into a ghost with 1/2 a red heart and flying, that is chained to your body for 10 seconds. This mechanic is very useful on Greed and Greedier modes, UNLOCK: Unlock this item by defeating Delirium in The Void floor with Keeper, *, orange, brown, yellow, gold, coin, cent, Upon use this item hurts Isaac without actually taking health away, allowing you to activate any items which trigger when taking damage without losing health, UNLOCK: Unlock this item by defeating Delirium on The Void floor with Eve, When used, this item permanently removes one of your red heart containers and gives you a flat +0.2 Damage Up, the Anemic effect (+1.5 Range Up + red creep trail) and a Cube of Meat, The Anemic effect will only last for the current room, but the Cube of Meat and Damage Up are both permanent, Only works for red hearts and has no effect when used if you only have soul/black hearts, Has no recharge time and can be used as often as you like, It is possible to generate multiple meatboys by stacking more than 4 Cubes of Meat, When used, this item gives you the effect of a random item for the rest of the room, Using this item multiple times in the same room will replace the previous item's effect with a new one, Certain items can be activated with this item which have unexpected effects and many items will do nothing, Items do not grant consumable drops which would normally occur when that item is picked up, Most flight-granting items have cosmetic effects only, and will not allow you to fly, Items that usually give HP up will not give extra health when gained from Metronome, UNLOCK: Unlock this item by defeating Greedier Mode with Eden, This dice allows you to press the Drop key to cycle between all possible dice effects and pick one to use, Charge time scales based on the chosen dice, updating every time you use it, Possible dice include: D1, D4, D6, D8, D10, D12, D20, D100. Sort: Item ID Colour Alphabetical Isaac Cheat Sheet. * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, When used, replaces all pedestal items in the current room with another random item. For more awesome indie content, subscribe to the channel here and follow me on Twitch for my livestreams!http://www.twitch.tv/pentahybridYou can also join ou. After dealing enough damage it will eventually disappear, At full size the flame deals 6x your tear damage, scaling down to 3x at its smallest size, The chance to for each tear to become a flame is affected by your luck stat and at +10 Luck it will activate 50% of the time (starts at 8.33% at +0 Luck), Each tear now has a small chance (3.33%) to be a needle instead, which deals 3 times your tear damage, If a needle hits a non-boss enemy it will instantly kill it and will explode into a circle of 10 more needles, The 10 spawned needles will also deal 3 times your tear damage, but won't instantly kill enemies or explode into more needles, The chance to for each tear to become a needle is affected by your luck stat and at +15 Luck it will activate 50% of the time, UNLOCK: Unlock this item by defeating Delirium in The Void floor with Lilith, *, black, syringe, injection, euthansia, dang, dan gheesling, dangheesling, dangDEB8, you piece, Upon entering a new room, Isaac will become camouflaged and enemies won't attack until you start firing tears, Camo Undies grants +0.5 speed while cloaked, When uncloaking, all nearby enemies take damage, and Isaac gains a brief tears + damage up, *, pink, purple, goggles underwear under wear, Any time a devil or angel room door opens after a boss, the other one will also spawn, The extra door will only spawn if a devil or angel room was randomly chosen to spawn already, After entering one of the doors, the other will disappear, If there isn't an available wall for the extra door to spawn on, only one door will spawn (i.e. Guarantees a Planetarium if an item room has been skipped, otherwise +15% chance for Planetariums to spawn while held. ?, Satan and The Lamb as Tainted Eden, Each brand new room, this trinket has a chance to transform into a copy of a random passive item, which gives you the effect for the duration of this room, UNLOCK: Unlock this trinket by defeating Mother as Tainted Eden, Gives a small chance to spawn a friendly Bony when clearing a room, which will throw bones at enemies until it takes enough damage to die, Can be either the regular white Bony or the black variant, UNLOCK: Unlock this trinket by defeating Isaac, ?? box, yellow, grey, When used, converts 1 soul/black heart into 1 red heart container, This item will take from your soul hearts first, REPENTANCE - Converter now only costs one soul heart to use (previously costed two), * shop room pool, shop item pool, the lost item pool, blue, gray, grey, yellow, sprocket, When used, this item will spawn a set of items or consumables based on which chapter you are currently on, Basement 1: 2 Soul hearts. Alternatively, you can just punch in "giveitem" followed by the item you want. When used, turns every normal enemy in the room into poop! The priority list of what will drop from champion enemies in order is as follows: Soul Hearts - When you have no red heart containers and less than 2 soul hearts, Red Hearts (Full hearts) - While at 0.5 red hearts, Red Hearts (Full hearts) - When you have at least half a red heart container empty, Trinkets - If you have no trinkets and there are no trinkets on the ground in the room, Soul Hearts - When you have less than 6 total heart containers of any kind, If none of the above conditions are true, champions will resume dropping their regular pickups, UNLOCK: Unlock this item by defeating Greedier mode with Maggy, Allows you to fire tears diagonally by holding down two of the fire buttons at once, If you are using a gamepad, this item allows you to fire in any direction, The first enemy you kill in each new room will now explode and poison all nearby enemies, causing them to take periodic damage until they also die and explode, If you have lots of enemies near each other this can cause a chain reaction, killing lots of enemies in one go, Gives Isaac a finger which floats infront of him and points in the same direction he is facing or firing. This one will be a hidden question mark, Allows you to see what both items are on alternative path floors (Downpour/Dross, Mines/Ashpit, Gehenna/Mausoleum), UNLOCK: Unlock this trinket by defeating challenge #40 (Seeing Double). REPENTANCE - Bob's Brain now has an increased delay before becoming available when entering rooms. Beyond the womb floor, replaces all coin and key spawns with a random pickup as follows: Bomb - 26.6% chance. * golden chest pool, gold chest pool, item room, treasure room, item room pool, green, ball, Both the box and trinket are consumed when this happens, UNLOCK: Unlock this trinket by defeating Isaac, ?? Each tick of poison damage is equal to your normal tear damage, Some random tears will gain the Rubber Cement effect and become bouncy, Grants +0.25 Speed, +0.75 Range, +0.1 Shot Speed, +0.2 Tears, +0.5 Damage and +1 Luck when Isaac's active item is fully charged, Infinite use items such as Potato Peeler count as charged and provide the bonus from this trinket, Grants +0.5 Speed, +1.5 Range, +0.3 Shot Speed, +0.4 Tears, +1.5 Damage when Isaac's active item is completely uncharged, One-time use items such as Mama Mega count as uncharged and provide the bonus from this trinket, Gives you another secret room on each new floor while held, Does not spawn more than one super secret room, only the normal secret room, *, purple, torn, ripped, paper, page, poster, When you have the same amount of coins, bombs and keys, half consumables turn into their doubled version, This effect works for any number of consumables, including 0 and 99, as long as the count for coins/keys/bombs is equal, Every time you take damage you have a very small chance to spawn a random pedestal item, When the effect triggers, the trinket is destroyed, Every time you take damage you have a very small chance to spawn the Lunch item, which gives +1 HP up, When the effect triggers, this trinket is destroyed, Increases the radius of any creep you produce, While held, any damage taken remove red hearts first, before soul hearts, black hearts and rotten heart damage, While at 1/2 of a red heart, it will begin to remove your other hearts again, UNLOCK: Unlock this item by beating Greedier mode with Eve, The Walnut has a chance to break when taking damage from an explosion. Does not apply to locked chests, * item room, treasure room, item room pool, red, horse shoe, Reveals the entire map for every floor except the secret room locations, Does not show the icons for any unexplored rooms, Can still help you to guess which direction the boss room is in, due to the fact that the Boss Room is usually in the room furthest away from the first room, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, Once you've beaten Mother once, a door will appear at the starting room in Depths II, which leads to the Mausoleum/Gehenna floors. smile, lil' brimstone, Prevents Isaac from taking any damage, but instead summons a familiar heart that follows you around. Spindown Dice is the only dice item that cannot be copied by the D Infinity. Effect persists between rooms while the time period is active, Speed Down - Reduces your speed stat by -0.12, Speed Up - Increases your speed stat by +0.15, Tears Down - Reduces your tears stat by -0.28, Tears Up - Increases your tears stat by 0.35, Telepills - Teleports you to a random room when used. Spindown Dice itself will be rerolled into Anima Sola, while Hypercoagulation rerolls into it. The door can only be opened if you have The Polaroid, The Negative or Faded Polaroid (the item/trinket is taken away when it opens). The Red Key item is required to access it, but it shows the direction to get there, UNLOCK: Unlock this item by defeating The Beast as Eve, Upon entering each new floor, if you have one red heart or less, another one is added, This effect works while moving up floors in the backwards path, This item has no effect for characters with non-red health i.e. Play The Binding of Isaac for free right now on Android. in Isaac? communion, the lost item pool, circle, cross, white, yellow, +0.04 Damage Up for every coin you currently have, At 99 coins this item gives +3.96 Damage Up, +0.04 per coin is the amount added before the damage formula is calculated, as this is the only way to show a consistent amount of damage given. Isaac's head will remain stationary and fire tears. Also works for opening Spiked Chests and Mimic Chests without taking damage, When used, this item restarts the game and places you back on the first floor with all your currently collected items, similar to doing a Victory Lap, Allows angel rooms to be found in the new run if a devil deal was taken in the first run, In Greed Mode and while playing as Tainted Keeper, this item costs 99 coins instead of 15.
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